How Long After Drinking Can I Take Hydrocodone
Ask A Pharmacist: Booze and Medications
The holiday flavour is filled with good spirits—both the type y'all can feel and the type y'all can beverage! With cease of the year celebrations quickly approaching, people living with HIV—in add-on to people taking medication for other weather condition—may wonder how alcohol affects their health and how it might interact with their medications. Here, I'll highlight some things to await out for if you lot're taking medications and plan on drinking, so that you can raise your glass in celebration with friends, family unit, and loved ones without worry.
About half of American adults report drinking on a regular basis—which we know tin be beneficial if it's done in moderation. Observational studies have pointed to benefits such as lowered risk of cardiovascular illness and better brain functioning in after years. On the other hand, excessive drinking increases chance of liver affliction, high blood pressure, diabetes, stroke and many other health conditions.
For nigh people, having some booze is usually okay, but heavy drinking can exist harmful. And we define heavy drinking as, for women, having iii or more drinks per day, or more than than vii drinks per calendar week. For men, heavy drinking ways having four or more than drinks per mean solar day or more than than fourteen drinks per week. Rampage drinking—when a larger quantity of alcohol is consumed in a curt period of time—can also be harmful.
Just what most drinking when you're taking medications? Is moderation withal the key?
This is 1 of the most common questions pharmacists get asked. And information technology's a great question—it's always important to know how booze may interact with the medications yous're taking since many medications don't mix well with alcohol. Booze can interfere with the way your body processes medications, change how medications piece of work in your trunk, or create or make side furnishings worse.
The good news is that in that location really aren't many directly effects of alcohol on how HIV medications are processed by your torso—then drinking in moderation is commonly okay if yous're taking antiretrovirals. That being said, at that place are a few things to be enlightened of if y'all're drinking more heavily.
Drinking alcohol increases the availability of abacavir (Ziagen, also independent in Trizivir, Epzicom, and Combivir) in your body by well-nigh 41%. This is not a large enough increment to crave a lower abacavir dose—but it does mean you're more likely to experience abacavir-related side effects. Then you should watch out for increased nausea or headache and exist certain to written report these to your medico if you feel them.
Heavy alcohol use with non-nucleoside reverse transcriptase inhibitors and protease inhibitors can cause hepatotoxicity (liver inflammation). Heavy alcohol use while taking didanosine (Videx) or stavudine (Zerit) tin also crusade or worsen peripheral neuropathy (nervus damage that causes tingling or pain in the limbs). If you're taking 1 of these medications, be sure to check in regularly with your doctor about how much and how frequently yous drink.
Having an occasional cocktail while taking HIV antiretrovirals usually will not crusade problems, but at that place are many other medications that can be harmful when mixed with alcohol.
Drinking alcohol if you're taking an over-the-counter coughing, cold, or allergy medicine like Benadryl, Zyrtec, or Robitussin can brand you feel more drowsy, light-headed, or sedated. There really isn't a hard and fast rule nigh how long to wait after taking 1 of these medications before having a drink. That's considering each of these medicines lasts a different amount of time in the torso, and each person may feel a different corporeality of drowsiness from them. The best thing to do in in this situation is to ask your customs chemist for advice. He or she will be able to give y'all individualized guidance based on the medication you lot're taking, your weight, and your gender.
Taking the pain medications oxycodone or Vicodin, the feet medications Klonopin and Ativan, or the muscle relaxer Flexeril before or after yous beverage can exist actually dangerous. These meds will increment the depressant effects of alcohol—slowing your animate, making you drowsy, and worsening your musculus control. If possible, avoid alcohol altogether if you are taking any of these medicines.
The over-the-counter medication acetaminophen (Tylenol) can cause really serious problems if information technology's used in the incorrect way with alcohol. Since this is such a common medication (and probable, ane that well-nigh people accept in their medicine cabinet) it's of import to empathize the circumstances when it tin cause wellness concerns.
You lot also shouldn't accept acetaminophen (Tylenol) on a regular basis if you lot drinkable booze regularly. Both alcohol and acetaminophen, separately, can harm your liver when used frequently over a long flow of time. But the combined effects of acetaminophen and alcohol can exist even worse—for your liver and for your kidneys. If you drinkable alcohol regularly, use another over-the-counter painkiller like ibuprofen, or apply acetaminophen sparingly. Or, if y'all're taking acetaminophen on a regular basis for chronic pain, you should try to limit your alcohol use to an occasional drinking glass. Remember, unless your doc tells y'all otherwise, y'all should not be taking whatsoever more than 3000 mg of acetaminophen per day, or 2000 mg if yous have liver disease.
If you lot're diabetic, drinking alcohol may produce very low blood carbohydrate levels up to six or eight hours later. This tin add together to the blood sugar-lowering furnishings of diabetes medications like glyburide or glipizide—making yous feel dizzy, weak, shaky, and tired. Drinking large amounts of booze if you're diabetic and taking these medicines may cause your blood sugar levels to drop dramatically, leading to a serious condition called ketoacidosis. This means you should potable alcohol only in moderation and bear snacks and your claret sugar monitor with yous.
Many high blood pressure level medications such as metoprolol, benazepril, and amlodipine may make you experience dizzy or drowsy if you drinkable alcohol. At that place's likewise a adventure of fainting associated with alcohol use and these medications.
Monoamine oxidase inhibitors (MAOIs) such as phenylzine, prescribed for low, don't interact well with alcohol. If you're taking an MAOI and drinking alcohol, at that place'southward a risk that you lot could feel a hypertensive crunch—when blood pressure rises to dangerous levels. This is a very serious condition that requires immediate, emergency medical treatment.
While these are the virtually mutual medications people accept that interact with alcohol, this list is not comprehensive. Then, if you take questions well-nigh your medications and how they mix with booze, it's all-time to check in with your doctor and your chemist. Knowing ahead of time how your meds will interact with alcohol will assistance you savor your holiday parties while taking care of your health.
Jennifer Cocohoba, PharmD, is an acquaintance clinical professor in the Schoolhouse of Pharmacy at the University of California, San Francisco (UCSF). Since 2004, she has worked as the clinical pharmacist for the UCSF Women's HIV Program, where she provides adherence support and medication information to patients and providers.
Selected References
Barve S., Kapoor R., Moghe A., and others. Focus on the Liver: Alcohol Utilize, Highly Agile Antiretroviral Therapy, and Liver Disease in HIV-Infected Patients.
Brown J.L. and others. Interventions to reduce alcohol use amongst HIV-Infected individuals: A review and critique of the literature. Current HIV/AIDS Reports 10(4): 356-370. Baronial thirty, 2013.
Hendershot C.S. and others. Alcohol utilize and antiretroviral adherence: Review and meta-analysis. Journal of Caused Allowed Deficiency Syndrome 52(ii): 180-202. October 1, 2009.
McNicholl I. HIV Insite Database of Antiretroviral Drug Interactions: Interactions with Ethanol (Booze, Ethanol, Wine, Liquor, Beer, Spirits) and Antiretrovirals.
National Institute on Booze Corruption and Alcoholism. Harmful interactions: Mixing alcohol with medicines.
U.S. Department of Agriculture and U.S. Department of Health and Human Services. Dietary Guidelines for Americans 2010.
Source: https://www.sfaf.org/collections/beta/ask-a-pharmacist-alcohol-and-medications/
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